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This drug also helps relieve chronic pain associated with cancer, nerve pain, or low-back pain. Generic tramadol tablets are available.<br> <h3><u>What should I tell my health care provider before I take this medicine?</u></h3><br> They need to know if you have any of these conditions:<br> • an alcohol or drug abuse problem<br> • breathing difficulty<br> • head injury or brain tumor<br> • kidney disease<br> • liver disease<br> • seizures (convulsions) or seizure disorder (epilepsy)<br> • stomach or intestinal problems<br> • an unusual or allergic reaction to tramadol, codeine, other pain medicines, foods, dyes, or preservatives<br> • pregnant or trying to get pregnant<br> • breast-feeding<br> <h3><u>How should I take this medicine?</u></h3><br> Take tramadol tablets by mouth. Follow the directions on the prescription label. Swallow the tablets with a drink of water. If tramadol upsets your stomach, take it with food or milk. 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Do not take double or extra doses.<br> <h3><u>What drug(s) may interact with tramadol?</u></h3><br> • alcohol<br> • antihistamines (commonly found in allergy or cold products)<br> • bupropion<br> • cocaine<br> • digoxin<br> • droperidol<br> • drugs to regulate heart rhythm such as amiodarone, propafenone, quinidine<br> • furazolidone<br> • imatinib<br> • isoniazid, INH<br> • linezolid<br> • medicines called MAO inhibitors-phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), selegiline (Eldepryl®)<br> • medicines for anxiety, depression, or sleeping problems<br> • medicines for nausea or vomiting<br> • medicines for Parkinson's disease such as entacapone, pramipexole, ropinirole or tolcapone<br> • medicines for mental problems like schizophrenia<br> • muscle relaxants<br> • naloxone<br> • other medicines for pain such as codeine, morphine, nalbuphine, pentazocine, or propoxyphene<br> • procarbazine<br> • rifampin<br> • ritonavir<br> • seizure medicines<br> • stimulants such as amphetamine or dextroamphetamine<br> • St. John's wort<br> • warfarin<br> <br> Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines. 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